|Other Names||NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4, Hormone-regulated proliferation-associated protein of 20 kDa, NDUFAF4, C6orf66, HRPAP20|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion.|
|Cellular Location||Mitochondrion. Membrane; Lipid-anchor|
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Provided below are standard protocols that you may find useful for product applications.
NADH:ubiquinone oxidoreductase (complex I) catalyzes thetransfer of electrons from NADH to ubiquinone (coenzyme Q) in thefirst step of the mitochondrial respiratory chain, resulting in thetranslocation of protons across the inner mitochondrial membrane.This gene encodes a complex I assembly factor. Mutations in thisgene are a cause of mitochondrial complex I deficiency. [providedby RefSeq].
Saada, A., et al. Am. J. Hum. Genet. 84(6):718-727(2009)Zimmermann, F.A., et al. Br. J. Cancer 100(9):1434-1437(2009)Saada, A., et al. Am. J. Hum. Genet. 82(1):32-38(2008)Tozlu-Kara, S., et al. J. Mol. Endocrinol. 39(4):305-318(2007)Karp, C.M., et al. Oncogene 26(12):1780-1788(2007)
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