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LILRB5 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O75023
Clone Names 100406079
Peptide ID 100406079
Additional Information
Gene ID 10990
Other Names Leukocyte immunoglobulin-like receptor subfamily B member 5, CD85 antigen-like family member C, Leukocyte immunoglobulin-like receptor 8, LIR-8, CD85c, LILRB5, LIR8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms LIR8
Function May act as receptor for class I MHC antigens.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Detected in a natural killer (NK) cells.
Research Areas
Citations (0)

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This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.


Davila, S., et al. Genes Immun. 11(3):232-238(2010)Tedla, N., et al. J. Leukoc. Biol. 83(2):334-343(2008)Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)Borges, L., et al. J. Immunol. 159(11):5192-5196(1997)

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Cat# BP13031c
Availability: Back Order
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