|Other Names||Transmembrane and coiled-coil domains protein 2, Cerebral protein 11, TMCC2, KIAA0481|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the regulation of the proteolytic processing of the amyloid precursor protein (APP) possibly also implicating APOE.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Concentrates in discrete patches along peripheral endoplasmic reticulum tubules|
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Provided below are standard protocols that you may find useful for product applications.
TMCC2 is a multi-pass membrane protein. It belongs to the TEX28 family. The function of TMCC2 remains unknown.
Soranzo, N., et al. Nat. Genet. 41(11):1182-1190(2009)Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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