|Other Names||Sodium-dependent phosphate transport protein 1, Na(+)/PI cotransporter 1, Na/Pi-4, Renal Na(+)-dependent phosphate cotransporter 1, Renal sodium-dependent phosphate transport protein 1, Renal sodium-phosphate transport protein 1, Sodium/phosphate cotransporter 1, Solute carrier family 17 member 1, SLC17A1, NPT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney (PubMed:27906618).|
|Cellular Location||Apical cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in kidney cortex, liver and brain but not in other tissues|
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Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane.
Iharada, M., et al. J. Biol. Chem. 285(34):26107-26113(2010)Gunjaca, G., et al. Croat. Med. J. 51(1):23-31(2010)Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)Shi, J., et al. Nature 460(7256):753-757(2009)Stark, K., et al. PLoS ONE 4 (11), E7729 (2009) :
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