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RARRES1 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P49788
Clone Names 100405063
Additional Information
Gene ID 5918
Other Names Retinoic acid receptor responder protein 1, Phorbol ester-induced gene 1 protein, PERG-1, RAR-responsive protein TIG1, Tazarotene-induced gene 1 protein, RARRES1, PEIG1, TIG1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13138b was selected from the C-term region of RARRES1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RARRES1
Synonyms PEIG1, TIG1
Function Inhibitor of the cytoplasmic carboxypeptidase AGBL2, may regulate the alpha-tubulin tyrosination cycle.
Cellular Location Membrane; Single- pass type III membrane protein. Secreted
Tissue Location Detected in urine (at protein level).
Research Areas
Citations (0)
citation

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Background

This gene was identified as a retinoid acid (RA)receptor-responsive gene. It encodes a type 1 membrane protein. Theexpression of this gene is upregulated by tazarotene as well as byretinoic acid receptors. The expression of this gene is found to bedownregulated in prostate cancer, which is caused by themethylation of its promoter and CpG island. Alternatively splicedtranscript variant encoding distinct isoforms have been observed.

References

Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :Kwok, W.K., et al. Cancer Genet. Cytogenet. 194(1):58-64(2009)Ohnishi, S., et al. Cell Prolif. 42(3):309-316(2009)Son, M.S., et al. Oncol. Res. 17 (11-12), 571-580 (2009) :Shutoh, M., et al. Cancer 104(8):1609-1619(2005)

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$ 277.78
Cat# BP13138b
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Availability: 2 weeks
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