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GAGE2B Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q13066
Clone Names 91216134
Additional Information
Gene ID 2574;645037
Other Names G antigen 2B/2C, GAGE-2B, GAGE-2C, Cancer/testis antigen 42, CT42, G antigen 2C, GAGE2B, GAGE2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13173a was selected from the N-term region of GAGE2B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GAGE2B
Synonyms GAGE2
Function Antigen, recognized on melanoma by autologous cytolytic T- lymphocytes.
Tissue Location Expressed in a variety of tumor tissues but not in normal tissues, except testis.
Research Areas
Citations (0)
citation

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Background

This gene belongs to a family of genes that are expressedin a variety of tumors but not in normal tissues, except for thetestis. The sequences of the family members are highly related butdiffer by scattered nucleotide substitutions. The antigenic peptideYRPRPRRY, which is also encoded by several other family members, isrecognized by autologous cytolytic T lymphocytes. [provided byRefSeq].

References

Sun, F., et al. Mol. Cancer Ther. 8(12):3191-3202(2009)Gjerstorff, M.F., et al. Tissue Antigens 71(3):187-192(2008)Ross, M.T., et al. Nature 434(7031):325-337(2005)De Backer, O., et al. Cancer Res. 59(13):3157-3165(1999)Scarcella, D.L., et al. Clin. Cancer Res. 5(2):335-341(1999)

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$ 277.78
Cat# BP13173a
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