|Other Names||Protocadherin-9, PCDH9|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13185b was selected from the C-term region of PCDH9. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Potential calcium-dependent cell-adhesion protein.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene belongs to the protocadherin gene family, asubfamily of the cadherin superfamily. The mRNA encodes acadherin-related neuronal receptor that localizes to synapticjunctions and is putatively involved in specific neuronalconnections and signal transduction. Sharing a characteristic withother protocadherin genes, this gene has a notably large exon thatencodes six cadherin domains and a transmembrane region. Twoalternatively spliced transcript variants encoding distinctisoforms have been found for this gene.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000)Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000)
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