|Other Names||Galactose-3-O-sulfotransferase 3, Gal3ST-3, 282-, Beta-galactose-3-O-sulfotransferase 3, Gal3ST3, Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3, GAL3ST3|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13192c was selected from the Center region of GAL3ST3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transfers a sulfate to position 3 of non-reducing beta- galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha- 1,3)GlcNAc and lower activity towards Gal-beta-1,3(Fuc-alpha- 1,4)GlcNAc.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein|
|Tissue Location||Highly expressed in thyroid, brain, kidney, heart and spinal cord.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of thegalactose-3-O-sulfotransferase protein family. The product of thisgene catalyzes sulfonation by transferring a sulfate group to the3' position of galactose in N-acetyllactosamine in both type 2(Gal-beta-1-4GlcNAc-R) oligosaccharides and core-2-branchedO-glycans, but not on type 1 or core-1-branched structures. Thisgene, which has also been referred to as GAL3ST2, is different fromthe GAL3ST2 gene located on chromosome 2 that encodes a relatedenzyme with distinct tissue distribution and substratespecificities, compared to galactose-3-O-sulfotransferase 3.
Chandrasekaran, E.V., et al. J. Biol. Chem. 279(11):10032-10041(2004)El-Fasakhany, F.M., et al. J. Biol. Chem. 276(29):26988-26994(2001)Seko, A., et al. J. Biol. Chem. 276(28):25697-25704(2001)Suzuki, A., et al. J. Biol. Chem. 276(26):24388-24395(2001)Chandrasekaran, E.V., et al. Glycoconj. J. 16(9):523-536(1999)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.