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GAL3ST3 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96A11
Clone Names 100406126
Peptide ID 100406126
Additional Information
Gene ID 89792
Other Names Galactose-3-O-sulfotransferase 3, Gal3ST-3, 282-, Beta-galactose-3-O-sulfotransferase 3, Gal3ST3, Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3, GAL3ST3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13192c was selected from the Center region of GAL3ST3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GAL3ST3
Function Transfers a sulfate to position 3 of non-reducing beta- galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha- 1,3)GlcNAc and lower activity towards Gal-beta-1,3(Fuc-alpha- 1,4)GlcNAc.
Cellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein
Tissue Location Highly expressed in thyroid, brain, kidney, heart and spinal cord.
Research Areas
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This gene encodes a member of thegalactose-3-O-sulfotransferase protein family. The product of thisgene catalyzes sulfonation by transferring a sulfate group to the3' position of galactose in N-acetyllactosamine in both type 2(Gal-beta-1-4GlcNAc-R) oligosaccharides and core-2-branchedO-glycans, but not on type 1 or core-1-branched structures. Thisgene, which has also been referred to as GAL3ST2, is different fromthe GAL3ST2 gene located on chromosome 2 that encodes a relatedenzyme with distinct tissue distribution and substratespecificities, compared to galactose-3-O-sulfotransferase 3.


Chandrasekaran, E.V., et al. J. Biol. Chem. 279(11):10032-10041(2004)El-Fasakhany, F.M., et al. J. Biol. Chem. 276(29):26988-26994(2001)Seko, A., et al. J. Biol. Chem. 276(28):25697-25704(2001)Suzuki, A., et al. J. Biol. Chem. 276(26):24388-24395(2001)Chandrasekaran, E.V., et al. Glycoconj. J. 16(9):523-536(1999)

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Cat# BP13192c
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