RTDR1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9UHP6 |
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Clone Names | 100406272 |
Gene ID | 27156 |
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Other Names | Rhabdoid tumor deletion region protein 1, RTDR1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13240a was selected from the N-term region of RTDR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | RSPH14 (HGNC:13437) |
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Synonyms | RTDR1 |
Function | Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia. |
Cellular Location | Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9D3W1} |
Tissue Location | Expressed in adult cerebellum, spinal cord, spleen, skeletal muscle and some/5 out of 9 rhabdoid tumors. Detected in fetal brain, lung, liver and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein with no known function butwith slight similarity to a yeast vacuolar protein. The gene islocated in a region deleted in pediatric rhabdoid tumors of thebrain, kidney and soft tissues, but mutations in this gene have notbeen associated with the disease.
References
Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :Zhou, J., et al. Gene 241(1):133-141(2000)
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