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ARSF Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P54793 |
|---|---|
| Clone Names | 100406288 |
| Gene ID | 416 |
|---|---|
| Other Names | Arylsulfatase F, ASF, 316-, ARSF |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13247c was selected from the Center region of ARSF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ARSF |
|---|---|
| Function | Exhibits arylsulfatase activity towards the artificial substrate 4-methylumbelliferyl sulfate. |
| Cellular Location | Secreted. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the sulfatase family, and morespecifically, the arylsulfatase subfamily. Members of the subfamilyshare similarity in sequence and splice sites, and are clusteredtogether on chromosome X, suggesting that they are derived fromrecent gene duplication events. Sulfatases are essential for thecorrect composition of bone and cartilage matrix. The activity ofthis protein, unlike that of arylsulfatase E, is not inhibited bywarfarin.
References
Cao, W., et al. J. Biol. Chem. 273(32):20629-20635(1998)Puca, A.A., et al. Genomics 42(2):192-199(1997)Parenti, G., et al. Curr. Opin. Genet. Dev. 7(3):386-391(1997)Franco, B., et al. Cell 81(1):15-25(1995)
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