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GFRA4 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9GZZ7
Clone Names 100406297
Peptide ID 100406297
Additional Information
Gene ID 64096
Other Names GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4, Persephin receptor, GFRA4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13249c was selected from the Center region of GFRA4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GFRA4
Function Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Cellular Location Isoform GFRalpha4a: Cell membrane; Lipid- anchor, GPI-anchor Isoform GFRalpha4c: Secreted.
Tissue Location Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the GDNFreceptor family. It is a glycosylphosphatidylinositol(GPI)-linkedcell surface receptor for persephin, and mediates activation of theRET tyrosine kinase receptor. This gene is a candidate gene forRET-associated diseases. Alternatively spliced transcript variantsencoding different isoforms have been described for this gene.


Yang, J., et al. FEBS Lett. 569 (1-3), 267-271 (2004) :Borrego, S., et al. J. Med. Genet. 40 (3), E18 (2003) :Deloukas, P., et al. Nature 414(6866):865-871(2001)Zhou, B., et al. Pediatr. Neurol. 25(2):156-161(2001)Lindahl, M., et al. J. Biol. Chem. 276(12):9344-9351(2001)

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Cat# BP13249c
Availability: Back Order
Bulk Size
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