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C17orf96 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession A6NHQ4
Clone Names 100408129
Peptide ID 100408129
Additional Information
Gene ID 100170841
Other Names Uncharacterized protein C17orf96, C17orf96
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13269c was selected from the Center region of C17orf96. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EPOP (HGNC:34493)
Function Scaffold protein that serves as a bridging partner between the PRC2/EED-EZH2 complex and the elongin BC complex: required to fine-tune the transcriptional status of Polycomb group (PcG) target genes in embryonic stem cells (ESCs). Plays a key role in genomic regions that display both active and repressive chromatin properties in pluripotent stem cells by sustaining low level expression at PcG target genes: acts by recruiting the elongin BC complex, thereby restricting excessive activity of the PRC2/EED-EZH2 complex. Interaction with USP7 promotes deubiquitination of H2B at promoter sites. Acts as a regulator of neuronal differentiation.
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q7TNS8}. Chromosome {ECO:0000250|UniProtKB:Q7TNS8}. Note=Localizes at both PRC2/EED-EZH2 sites (H3K27me3) and broad H3K4me3 sites on chromatin of embryonic stem cells (ESCs) {ECO:0000250|UniProtKB:Q7TNS8}
Research Areas
Citations (0)

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Background

The specific function of this protein remains unknown.

References

Zody, M.C., et al. Nature 440(7087):1045-1049(2006)

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Cat# BP13269c
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