PI15 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O43692 |
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Clone Names | 100416091 |
Gene ID | 51050 |
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Other Names | Peptidase inhibitor 15, PI-15, 25 kDa trypsin inhibitor, p25TI, Cysteine-rich secretory protein 8, CRISP-8, SugarCrisp, PI15, CRISP8, P25TI |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13330a was selected from the N-term region of PI15. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PI15 |
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Synonyms | CRISP8, P25TI |
Function | Serine protease inhibitor which displays weak inhibitory activity against trypsin (PubMed:8882727). May play a role in facial patterning during embryonic development (By similarity). |
Cellular Location | Secreted. |
Tissue Location | Weakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a trypsin inhibitor. The protein sharessimilarity to insect venom allergens, mammalian testis-specificproteins and plant pathogenesis-related proteins. It is frequentlyexpressed in human neuroblastoma and glioblastoma cell lines, andthus may play a role in the central nervous system. [provided byRefSeq].
References
Melzer, D., et al. PLoS Genet. 4 (5), E1000072 (2008) :Kaplan, F., et al. Am. J. Physiol. 276 (6 PT 1), L1027-L1036 (1999) :Yamakawa, T., et al. Biochim. Biophys. Acta 1395(2):202-208(1998)Yamakawa, T., et al. Biochim. Biophys. Acta 1395(2):202-208(1998)Koshikawa, N., et al. J. Biochem. 119(2):334-339(1996)
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