BEAN Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q3B7T3 |
---|---|
Clone Names | 91201147 |
Gene ID | 146227 |
---|---|
Other Names | Protein BEAN1, Brain-expressed protein associating with Nedd4 homolog, BEAN, BEAN1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13386a was selected from the N-term region of BEAN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | BEAN1 |
---|---|
Cellular Location | Membrane; Single-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is one of severalproteins that interact with NEDD4, a member of a family ofubiquitin-protein ligases. These proteins have PY motifs in commonthat bind to the WW domains of NEDD4. NEDD4 is developmentallyregulated, and is highly expressed in embryonic tissues. Mutationsin this gene (i.e., intronic insertions of >100 copies ofpentanucleotide repeats including a (TGGAA)n sequence) areassociated with spinocerebellar ataxia type 31. Alternativelyspliced transcript variants encoding different isoforms have beenfound for this gene.
References
Sato, N., et al. Am. J. Hum. Genet. 85(5):544-557(2009)Jolliffe, C.N., et al. Biochem. J. 351 PT 3, 557-565 (2000) :
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.