Periostin/OSF-2, murine recombinant protein
OSF-2, Periostin, Osteoblast Specific Factor 2, PN OSF-2,PDLPOSTN, POSTN, MGC119510, MGC119511, PN,
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q62009 |
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Calculated MW | 85 kDa |
Gene ID | 50706 |
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Gene Symbol | POSTN |
Other Names | OSF-2, Periostin, Osteoblast Specific Factor 2, PN OSF-2, PDLPOSTN, POSTN, MGC119510, MGC119511, PN, RP11-412K4.1. |
Gene Source | Mouse |
Source | CHO cells |
Assay&Purity | SDS-PAGE; ≥95% |
Assay2&Purity2 | HPLC; ≥95% |
Recombinant | Yes |
Target/Specificity | Periostin/OSF-2 |
Application Notes | Reconstitute with 100 µl sterile water (concentration of 0.1 mg/ml after reconstitution) |
Format | Lyophilized protein |
Storage | -20°C; Solid (Lyophilized from PBS) |
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Background
Periostin was originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor β1 (TGF-β1) and bone morphogenetic protein (BMP-2). Abnormal expression of periostin is also linked to angiogenesis and metastasis in epithelial tumors. BioVision’s Mouse periostin (aa 24-783) (isoform 5) is fused at the C-terminus to a FLAG®-tag.
References
Takeshita S.,et al.Biochem. J. 294:271-278(1993).
Carninci P.,et al.Science 309:1559-1563(2005).
Horiuchi K.,et al.J. Bone Miner. Res. 14:1239-1249(1999).
Sugiura T.,et al.Protein Expr. Purif. 6:305-311(1995).
Kruzynska-Frejtag A.,et al.Mech. Dev. 103:183-188(2001).
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