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Relaxin-2 Antibody

Rabbit Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P04090
Other Accession AAI26420.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 21043 Da
Additional Information
Gene ID 6019
Application & Usage Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~21 kDa Relaxin-2 in samples from human origins. Reaction to other species has not been tested. A ~100 kDa unknown band can also be detected.
Other Names Relaxin2, Relaxin-2, Relaxin 2 , RLN2
Target/Specificity Relaxin-2
Antibody Form Liquid
Appearance Colorless liquid
Formulation 200 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsRelaxin-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RLN2
Function Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
Cellular Location Secreted.
Tissue Location Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary
Research Areas
Citations (0)
citation

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Background

Relaxin 2 is a peptide hormone produced by the copora lutea of the ovary during pregnancy in many mammalian species. It is secreted into the blood just before parturition to help facilitate the birth process. Like insulin, relaxin is a heterodimer of two peptide chains A and B that are covalently linked by disulfide bonds.

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Discontinued
Cat# ABV10700-30
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