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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   PHOX2B Antibody   

PHOX2B Antibody

Rabbit Polyclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q99453
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 31621 Da
Additional Information
Gene ID 8929
Positive Control Mouse liver tissue lysates
Application & Usage The antibody can be used for ELISA (1:1,000) and Western blotting (1: 100~500).
Other Names Neuroblastoma Phox, NBPhox
Target/Specificity PHOX2B
Antibody Form Liquid
Appearance Colorless liquid
Formulation Supplied in PBS with 0.09% (W/V) sodium azide at a concentration of 0.25 mg/ml. This antibody is purified thro µgh a protein A column, followed by peptide affinity purification.
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsPHOX2B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHOX2B
Synonyms PMX2B
Function Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta- hydrolase and c-fos promoters, and of several enhancers including cAMP- response element and serum-response element.
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Tissue Location Expressed in neuroblastoma, brain and adrenal gland
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.

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Cat# ABV10710-100
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Ordering Information

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