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IL-19 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8CJ70 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 20288 Da |
| Gene ID | 329244 |
|---|---|
| Positive Control | Recombinant murine IL-19 |
| Application & Usage | The antibody can be used in Western Blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant murine IL-19 can be used as a positive control. |
| Other Names | Interleukin-19, IL19 |
| Target/Specificity | IL-19 |
| Antibody Form | Liquid |
| Appearance | Colorless liquid |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit anti-murine IL-19 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal. |
| Handling | The antibody solution should be gently mixed before use. |
| Reconstitution & Storage | -20 °C |
| Background Descriptions | |
| Precautions | IL-19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Il19 |
|---|---|
| Function | Cytokine that functions as an anti-inflammatory and proangiogenic factor (PubMed:12370360, PubMed:27053520). Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up- regulation of IL4 and IL5 (PubMed:15557163). Produced by osteocytes, stimulates granulopoiesis and neutrophil formation (PubMed:33684929). Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3 (By similarity). |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
IL-19 is a single, non-glycosylated polypeptide with 152 amino acids. It plays an important role in regulating development and functioning of the skin .
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