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VEGF-C Antibody

Purified Rabbit Polyclonal Antibody

     
  • WB - VEGF-C Antibody ABV11610-30
    Western blot analysis using recombinant murine VEGF-c. Lane1: 50ng; Lane2: 100ng; Lane3: 200ng.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P97953
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 46471 Da
Additional Information
Gene ID 22341
Other Names VEGF C, Vascular Endothelial Growth Factor C , Vascular endothelial growth factor-related protein C; VRP
Target/Specificity VEGF- C
Formulation 100 µg (0.5 mg/ml) affinity purified rabbit anti-murine VEGF-C polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
Handling The antibody solution should be gently mixed before use.
Background Descriptions
PrecautionsVEGF-C Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Vegfc
Function Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors.
Cellular Location Secreted.
Tissue Location Expressed in adult heart, brain, spleen, lung, liver, skeletal muscle, kidney, testis and intestine with higher levels in heart, brain and kidney. Isoform 4 levels are very low. Isoform 3 is mostly expressed in liver and has reduced expression level in other tissues. Isoform 2 is mostly expressed in brain and kidney, although a lower level expression in other tissues is also detectable
Research Areas
Citations (0)
citation

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Background

Vascular Endothelial Growth Factor-C (VEGF-C) is a 125 amino acid protein that plays an important role in angiogenesis and many other biological processes. Human VEGF-C exhibits about 85% homology with murine VEGF-C.

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Discontinued
Cat# ABV11610-30
Size:

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