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Anti-Mannose Phosphate Isomerase Antibody (4G9-B4-B8)

Mouse Monoclonal Antibody

     
  • WB - Anti-Mannose Phosphate Isomerase Antibody (4G9-B4-B8)                                       
 ABV12060-100
    Western blot detection of Mannose Phosphate Isomerase in Rat brain, Rat kidney, A549 and LNCAP cell tysates using Mannose Phosphate Isomerase mouse mAb
    detail
  • ICC - Anti-Mannose Phosphate Isomerase Antibody (4G9-B4-B8)                                       
 ABV12060-100
    Immunocytochemistry stain of HeLa using Mannose Phosphate Isomerase mouse mAb
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF
Primary Accession P34949
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Isotype Mouse IgG1
Clone Names 4G9-B4-B8
Calculated MW 46656 Da
Additional Information
Gene ID 4351
Application & Usage WB: Rat kidney, Rat brain, A549 and Lncap cell lysates; IF: HeLa cells
Other Names Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI
Target/Specificity Mannose Phosphate Isomerase
Antibody Form Liquid
Appearance Colorless liquid
Formulation In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
Handling The antibody solution should be gently mixed before use.
Reconstitution & Storage -20 °C
Background Descriptions
PrecautionsAnti-Mannose Phosphate Isomerase Antibody (4G9-B4-B8) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPI (HGNC:7216)
Synonyms PMI1
Function Isomerase that catalyzes the interconversion of fructose-6-P and mannose-6-P and has a critical role in the supply of D-mannose derivatives required for many eukaryotic glycosylation reactions.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q924M7}.
Tissue Location Expressed in all tissues, but more abundant in heart, brain and skeletal muscle.
Research Areas
Citations (0)
citation

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Background

Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.

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Discontinued
Cat# ABV12060-100
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