Anti-Mannose Phosphate Isomerase Antibody (4G9-B4-B8)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF |
---|---|
Primary Accession | P34949 |
Reactivity | Human, Rat |
Host | Mouse |
Clonality | Monoclonal |
Isotype | Mouse IgG1 |
Clone Names | 4G9-B4-B8 |
Calculated MW | 46656 Da |
Gene ID | 4351 |
---|---|
Application & Usage | WB: Rat kidney, Rat brain, A549 and Lncap cell lysates; IF: HeLa cells |
Other Names | Mannose-6-phosphate isomerase, Phosphohexomutase, Phosphomannose isomerase, PMI |
Target/Specificity | Mannose Phosphate Isomerase |
Antibody Form | Liquid |
Appearance | Colorless liquid |
Formulation | In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol |
Handling | The antibody solution should be gently mixed before use. |
Reconstitution & Storage | -20 °C |
Background Descriptions | |
Precautions | Anti-Mannose Phosphate Isomerase Antibody (4G9-B4-B8) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MPI (HGNC:7216) |
---|---|
Synonyms | PMI1 |
Function | Isomerase that catalyzes the interconversion of fructose-6-P and mannose-6-P and has a critical role in the supply of D-mannose derivatives required for many eukaryotic glycosylation reactions. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q924M7}. |
Tissue Location | Expressed in all tissues, but more abundant in heart, brain and skeletal muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.