|Other Accession||NM_003262, NP_003253|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||Dtrp1, FLJ32803, HTP1, TLOC1, TP-1|
|Other Names||Translocation protein SEC62, Translocation protein 1, TP-1, hTP-1, SEC62, TLOC1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-SEC62 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SEC62 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Daimon M.,et al.Biochem. Biophys. Res. Commun. 230:100-104(1997).
Daimon M.,et al.IUBMB Life 48:619-624(1999).
Meyer H.-A.,et al.J. Biol. Chem. 275:14550-14557(2000).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Olsen J.V.,et al.Cell 127:635-648(2006).
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