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HTR1E / 5-HT1E Receptor Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

     
  • IHC - HTR1E / 5-HT1E Receptor Antibody (Cytoplasmic Domain) ALS10578
    Anti-5HT1E Receptor antibody ALS10578 IHC of human testis.
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  • SPECIFICATION
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P28566
Reactivity Human, Monkey, Horse, Bovine, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 42kDa
Dilution IHC-P (16-24 µg/ml)
Additional Information
Gene ID 3354
Other Names 5-hydroxytryptamine receptor 1E, 5-HT-1E, 5-HT1E, S31, Serotonin receptor 1E, HTR1E
Target/Specificity Human 5HT1E Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsHTR1E / 5-HT1E Receptor Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HTR1E
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Detected in brain..
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

References

McAllister G.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:5517-5521(1992).
Levy F.O.,et al.FEBS Lett. 296:201-206(1992).
Zgombick J.M.,et al.Mol. Pharmacol. 42:180-185(1992).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Mungall A.J.,et al.Nature 425:805-811(2003).

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Discontinued
Cat# ALS10578
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