Dipeptidylpeptidase 10 / DPP10 Antibody (Extracellular Domain)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q8N608 |
Reactivity | Human, Rabbit, Monkey, Pig, Horse, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 91kDa |
Dilution | IHC-P (20 µg/ml) |
Gene ID | 57628 |
---|---|
Other Names | Inactive dipeptidyl peptidase 10, Dipeptidyl peptidase IV-related protein 3, DPRP-3, Dipeptidyl peptidase X, DPP X, Dipeptidyl peptidase-like protein 2, DPL2, DPP10, DPRP3, KIAA1492 |
Target/Specificity | Human DPP10. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Reconstitution & Storage | Long term: -70°C; Short term: +4°C |
Precautions | Dipeptidylpeptidase 10 / DPP10 Antibody (Extracellular Domain) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DPP10 |
---|---|
Synonyms | DPRP3, KIAA1492 |
Function | Promotes cell surface expression of the potassium channel KCND2 (PubMed:15454437). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:15454437). Has no dipeptidyl aminopeptidase activity (PubMed:12662155). |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q6NXK7, ECO:0000269|PubMed:14566338}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P42658} |
Tissue Location | Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands |
Volume | 50 µl |
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Background
Has no dipeptidyl aminopeptidase activity. May modulate cell surface expression and activity of the potassium channels KCND1 and KCND2.
References
Chen T.,et al.Adv. Exp. Med. Biol. 524:79-86(2003).
Qi S.Y.,et al.Biochem. J. 373:179-189(2003).
Allen M.,et al.Nat. Genet. 35:258-263(2003).
Takimoto K.,et al.Biochem. Biophys. Res. Commun. 348:1094-1100(2006).
Nagase T.,et al.DNA Res. 7:143-150(2000).
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