THRSP Antibody
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | Q92748 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 17kDa |
Dilution | IHC-P (3.75 µg/ml) |
Gene ID | 7069 |
---|---|
Other Names | Thyroid hormone-inducible hepatic protein, Spot 14 protein, S14, SPOT14, THRSP |
Target/Specificity | Human THRSP. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | THRSP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | THRSP |
---|---|
Function | Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. |
Cellular Location | Nucleus. Cytoplasm |
Tissue Location | Mainly expressed in tissues that synthesize triglycerides |
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Background
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (By similarity). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
References
Grillasca J.-P.,et al.FEBS Lett. 401:38-42(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Chou W.Y.,et al.Biochem. Biophys. Res. Commun. 357:133-138(2007).
Chou W.Y.,et al.Int. J. Biochem. Cell Biol. 40:1826-1834(2008).
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