GMPS / GMP Synthase Antibody (clone 1D10)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P49915 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 1D10 |
Calculated MW | 77kDa |
Dilution | IHC-P (5 µg/ml) |
Gene ID | 8833 |
---|---|
Other Names | GMP synthase [glutamine-hydrolyzing], 6.3.5.2, GMP synthetase, Glutamine amidotransferase, GMPS |
Reconstitution & Storage | Store at -20°C. Aliquot to avoid freeze/thaw cycles. |
Precautions | GMPS / GMP Synthase Antibody (clone 1D10) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GMPS |
---|---|
Function | Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate. |
Cellular Location | Cytoplasm, cytosol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.
References
Hirst M.,et al.J. Biol. Chem. 269:23830-23837(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Pegram L.D.,et al.Blood 96:4360-4362(2000).
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