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DPPL1 / PPAPDC1B Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q8NEB5 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 29kDa |
| Dilution | IHC-P (5 µg/ml), WB (1-2 µg/ml), |
| Gene ID | 84513 |
|---|---|
| Other Names | Phosphatidate phosphatase PPAPDC1B, 3.1.3.4, Phosphatidic acid phosphatase type 2 domain-containing protein 1B, PPAPDC1B, DPPL1, HTPAP |
| Target/Specificity | Human PPAPDC1B |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | DPPL1 / PPAPDC1B Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLPP5 (HGNC:25026) |
|---|---|
| Function | Magnesium-independent phospholipid phosphatase with broad substrate specificity (PubMed:17590538). Preferentially catalyzes the conversion of diacylglycerol pyrophosphate into phosphatidate but can also act on phosphatidate and lysophosphatidate (PubMed:17590538). Phospholipid phosphatases are involved in both the synthesis of lipids and the generation or degradation of lipid-signaling molecules (PubMed:17590538). |
| Cellular Location | Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q3UMZ3} |
| Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma.
References
Takeuchi M.,et al.Gene 399:174-180(2007).
Nusbaum C.,et al.Nature 439:331-335(2006).
Li Y.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Wu X.,et al.Oncogene 25:1832-1840(2006).
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