FKBP25 / FKBP3 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q00688 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 25kDa |
Dilution | IHC-P (5 µg/ml), WB (1:500-1:3000), |
Gene ID | 2287 |
---|---|
Other Names | Peptidyl-prolyl cis-trans isomerase FKBP3, PPIase FKBP3, 5.2.1.8, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-25, FK506-binding protein 3, FKBP-3, Immunophilin FKBP25, Rapamycin-selective 25 kDa immunophilin, Rotamase, FKBP3, FKBP25 |
Target/Specificity | Human FKBP25. Predicted cross-reactivity based on amino acid sequence homology: mouse (93%), rat (94%), bovine (97%). |
Reconstitution & Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
Precautions | FKBP25 / FKBP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FKBP3 |
---|---|
Synonyms | FKBP25 |
Function | FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins. |
Cellular Location | Nucleus. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
References
Wiederrecht G.,et al.Biochem. Biophys. Res. Commun. 185:298-303(1992).
Hung D.T.,et al.Biochem. Biophys. Res. Commun. 184:733-738(1992).
Jin Y.-J.,et al.J. Biol. Chem. 267:10942-10945(1992).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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