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MD-1 / LY86 Antibody (aa112-125)

Rabbit Polyclonal Antibody

     
  • WB - MD-1 / LY86 Antibody (aa112-125) ALS14559
    Western blot of MD-1 in cell lysates from Ramos using antibody at 2 ug/ml dilution.
    detail
  • IHC - MD-1 / LY86 Antibody (aa112-125) ALS14559
    Anti-LY86 / MD-1 antibody IHC of human spleen.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP
Primary Accession O95711
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 18kDa
Dilution IHC-P (10 µg/ml), IP (2 µg/ml), WB (2 µg/ml)
Additional Information
Gene ID 9450
Other Names Lymphocyte antigen 86, Ly-86, Protein MD-1, LY86, MD1
Target/Specificity A KLH-conjugated synthetic peptide corresponding to amino acids 112-125 of human MD-1.
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsMD-1 / LY86 Antibody (aa112-125) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LY86
Synonyms MD1
Function May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).
Cellular Location Secreted, extracellular space. Note=Associated with CD180 at the cell surface
Tissue Location Highly expressed in B-cells, monocytes and tonsil.
Research Areas
Citations (0)
citation

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Background

May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression (By similarity).

References

Miura Y.,et al.Blood 92:2815-2822(1998).
Begum N.A.,et al.Biochem. Biophys. Res. Commun. 256:325-329(1999).
Mungall A.J.,et al.Nature 425:805-811(2003).
Zhang Z.,et al.Protein Sci. 13:2819-2824(2004).
Ohto U.,et al.J. Mol. Biol. 413:815-825(2011).

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$ 467.50
Cat# ALS14559
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