MTNR1B / MT2 Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | P49286 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 40kDa |
Dilution | ELISA (1:32000), IHC-P (3.75 µg/ml), |
Gene ID | 4544 |
---|---|
Other Names | Melatonin receptor type 1B, Mel-1B-R, Mel1b receptor, MTNR1B |
Target/Specificity | Human MTNR1B. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | MTNR1B / MT2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MTNR1B |
---|---|
Function | High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Expressed in retina and less in brain and hippocampus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
References
Reppert S.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:8734-8738(1995).
Ebisawa T.,et al.Neurosci. Lett. 280:29-32(2000).
King M.M.,et al.Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
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