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EPS8L2 Antibody (aa1-50)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9H6S3 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 81kDa |
| Dilution | ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000) |
| Gene ID | 64787 |
|---|---|
| Other Names | Epidermal growth factor receptor kinase substrate 8-like protein 2, EPS8-like protein 2, Epidermal growth factor receptor pathway substrate 8-related protein 2, EPS8-related protein 2, EPS8L2, EPS8R2 |
| Target/Specificity | ES8L2 Antibody detects endogenous levels of total ES8L2 protein. |
| Reconstitution & Storage | Store at -20°C for up to one year. |
| Precautions | EPS8L2 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | EPS8L2 |
|---|---|
| Synonyms | EPS8R2 |
| Function | Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells (By similarity). |
| Cellular Location | Cytoplasm. Cell projection, stereocilium {ECO:0000250|UniProtKB:Q99K30}. Note=Localizes at the tips of the stereocilia of the inner and outer hair cells {ECO:0000250|UniProtKB:Q99K30} |
| Tissue Location | Detected in fibroblasts and placenta. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.
References
Tocchetti A.,et al.Genomics 81:234-244(2003).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
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