CALCR / Calcitonin Receptor Antibody (clone 2F7)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P30988 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2F7 |
Calculated MW | 59kDa |
Dilution | IHC-P (10 µg/ml) |
Gene ID | 799 |
---|---|
Other Names | Calcitonin receptor, CT-R, CALCR |
Target/Specificity | Human CALCR / Calcitonin Receptor |
Reconstitution & Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | CALCR / Calcitonin Receptor Antibody (clone 2F7) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CALCR (HGNC:1440) |
---|---|
Function | This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.
References
Gorn A.H.,et al.J. Clin. Invest. 90:1726-1735(1992).
Kuestner R.E.,et al.Mol. Pharmacol. 46:246-255(1994).
Albrandt K.,et al.Endocrinology 136:5377-5384(1995).
Frendo J.L.,et al.FEBS Lett. 342:214-216(1994).
Nishikawa T.,et al.FEBS Lett. 458:409-414(1999).
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