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CALCR / Calcitonin Receptor Antibody (clone 2F7)

Mouse Monoclonal Antibody

     
  • IHC - CALCR / Calcitonin Receptor Antibody (clone 2F7) ALS16115
    Anti-CALCR / Calcitonin Receptor antibody IHC staining of human small intestine.
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  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P30988
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2F7
Calculated MW 59kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 799
Other Names Calcitonin receptor, CT-R, CALCR
Target/Specificity Human CALCR / Calcitonin Receptor
Reconstitution & Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCALCR / Calcitonin Receptor Antibody (clone 2F7) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CALCR (HGNC:1440)
Function This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.
Cellular Location Cell membrane; Multi-pass membrane protein.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.

References

Gorn A.H.,et al.J. Clin. Invest. 90:1726-1735(1992).
Kuestner R.E.,et al.Mol. Pharmacol. 46:246-255(1994).
Albrandt K.,et al.Endocrinology 136:5377-5384(1995).
Frendo J.L.,et al.FEBS Lett. 342:214-216(1994).
Nishikawa T.,et al.FEBS Lett. 458:409-414(1999).

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Discontinued
Cat# ALS16115
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