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ACSL6 Antibody (aa499-548)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9UKU0 |
| Other Accession | 23305 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 77752 Da |
| Dilution | ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500 - 1:1000), |
| Gene ID | 23305 |
|---|---|
| Other Names | ACSL6, ACS2, FACL6, LACS 6, LACS2, KIAA0837, LACS5 |
| Target/Specificity | ACSL6 Antibody detects endogenous levels of total ACSL6 protein. |
| Reconstitution & Storage | PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year. |
| Precautions | ACSL6 Antibody (aa499-548) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ACSL6 (HGNC:16496) |
|---|---|
| Function | Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:22633490, PubMed:24269233). Plays an important role in fatty acid metabolism in brain and the acyl- CoAs produced may be utilized exclusively for the synthesis of the brain lipid. |
| Cellular Location | Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein |
| Tissue Location | Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
References
Malhotra K.T.,et al.Biochem. J. 344:135-143(1999).
Yagasaki F.,et al.Genes Chromosomes Cancer 26:192-202(1999).
Soupene E.,et al.BMC Mol. Biol. 7:21-21(2006).
Nagase T.,et al.DNA Res. 5:355-364(1998).
Li W.B.,et al.Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
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