OXER1 Antibody (aa212-261)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q8TDS5 |
Other Accession | 165140 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 41426 Da |
Dilution | ELISA (1:10000), IF (1:100 - 1:500), IHC-P (5 µg/ml), WB (1:500 - 1:1000), |
Gene ID | 165140 |
---|---|
Other Names | OXER1, GPR170, G-protein coupled receptor 170, HEOAD54, Oxoeicosanoid (OXE) receptor 1, Oxoeicosanoid receptor 1, TG1019 |
Target/Specificity | OXER1 Antibody detects endogenous levels of total OXER1 protein. |
Reconstitution & Storage | PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol. Store at -20°C for up to one year. |
Precautions | OXER1 Antibody (aa212-261) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OXER1 |
---|---|
Synonyms | GPR170, TG1019 |
Function | Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)- hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. |
Cellular Location | Membrane; Multi-pass membrane protein |
Tissue Location | Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.
References
Hosoi T.,et al.J. Biol. Chem. 277:31459-31465(2002).
Jones C.E.,et al.Mol. Pharmacol. 63:471-477(2003).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Takeda S.,et al.FEBS Lett. 520:97-101(2002).
Hillier L.W.,et al.Nature 434:724-731(2005).
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