PYGL Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P06737 |
Other Accession | 5836 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 97149 Da |
Dilution | IHC-P (10 µg/ml), |
Gene ID | 5836 |
---|---|
Other Names | PYGL, GPLL, Phosphorylase, glycogen liver, Phosphorylase, glycogen, liver, GSD6 |
Target/Specificity | Human PYGL |
Reconstitution & Storage | PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
Precautions | PYGL Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PYGL (HGNC:9725) |
---|---|
Function | Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. |
Cellular Location | Cytoplasm, cytosol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
References
Newgard C.B.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8132-8136(1986).
Carty M.D.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Chang S.,et al.Hum. Mol. Genet. 7:865-870(1998).
Burwinkel B.,et al.Am. J. Hum. Genet. 62:785-791(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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