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PYGL Antibody

Rabbit Polyclonal Antibody

     
  • IHC-P - PYGL Antibody ALS17263
    Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
    detail
  • IHC-P - PYGL Antibody ALS17263
    Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P06737
Other Accession 5836
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 97149 Da
Dilution IHC-P (10 µg/ml),
Additional Information
Gene ID 5836
Other Names PYGL, GPLL, Phosphorylase, glycogen liver, Phosphorylase, glycogen, liver, GSD6
Target/Specificity Human PYGL
Reconstitution & Storage PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsPYGL Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PYGL (HGNC:9725)
Function Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Cellular Location Cytoplasm, cytosol.
Research Areas
Citations (0)
citation

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Background

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

References

Newgard C.B.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8132-8136(1986).
Carty M.D.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Chang S.,et al.Hum. Mol. Genet. 7:865-870(1998).
Burwinkel B.,et al.Am. J. Hum. Genet. 62:785-791(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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Discontinued
Cat# ALS17263
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