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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-GRM5 / MGLUR5 Antibody (C-Terminus)
Anti-GRM5 / MGLUR5 Antibody (C-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, Flo |
|---|---|
| Primary Accession | P41594 |
| Predicted | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 132469 Da |
| Dilution | Flo (1 - 3 µg/10E6 cells), IHC-P (10 µg/ml), WB (1 - 2 µg/ml) |
| Gene ID | 2915 |
|---|---|
| Alias Symbol | GRM5 |
| Other Names | GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5 |
| Target/Specificity | Endogenous levels of human mGluR5. It is predicted to react with mouse and rat mGluR5 protein according to sequence homology. Positive Control: Ramos. |
| Reconstitution & Storage | Lyophilized from PBS, pH 7.4, 0.02% sodium azide. Store lyophilized at -20°C. The reconstituted product can be stored for short term at 4 °C or long term at -20 °C or below. Avoid freeze/thaw cycles. |
| Precautions | Anti-GRM5 / MGLUR5 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRM5 |
|---|---|
| Synonyms | GPRC1E, MGLUR5 |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol- calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
Research Areas
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Application Protocols
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