Anti-CCR3 Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P51677 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 41044 Da |
Dilution | ELISA, IHC-P (2.5 µg/ml), WB |
Gene ID | 1232 |
---|---|
Alias Symbol | CCR3 |
Other Names | CCR3, C-C chemokine receptor type 3, B-chemokine receptor, CD193, CD193 antigen, Chemokine c-c motif receptor 3, C-C chemokine receptor 3, CKR3, CC-CKR-3, CCR-3, CMKBR3, Eosinophil eotaxin receptor, Eotaxin receptor, C-C CKR-3, CC chemokine receptor 3 |
Target/Specificity | 14 amino acid peptide from near the amino terminus of human CCR3 |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-CCR3 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCR3 |
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Synonyms | CMKBR3 |
Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064). Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed:8676064). In addition acts as a possible functional receptor for NARS1 (PubMed:30171954). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | In eosinophils as well as trace amounts in neutrophils and monocytes. |
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