Anti-LGI3 Antibody (Internal)
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q8N145 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 61704 Da |
Dilution | IHC-P (5 µg/ml), WB (1 - 2 µg/ml) |
Gene ID | 203190 |
---|---|
Alias Symbol | LGI3 |
Other Names | LGI3, LGIL4, LGI1-like protein 4 |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-LGI3 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LGI3 |
---|---|
Synonyms | LGIL4 |
Function | May participate in the regulation of neuronal exocytosis. |
Cellular Location | Secreted. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:Q8K406}. Synapse, synaptosome {ECO:0000250|UniProtKB:Q8K406}. Cell projection, axon {ECO:0000250|UniProtKB:Q8K406}. Note=Found in the synaptosomal membrane fraction. Within peripheral myelinated axons, LGI3 is highly expressed at the juxtaparanodal membrane and colocalizes with the voltage-gated potassium channels Kv1.1 (KCNA1) and Kv1.2 (KCNA2), and with CNTNAP2, DLG4, ADAM22 and ADAM23 (By similarity) {ECO:0000250|UniProtKB:Q8K406} |
Tissue Location | Widely expressed, with highest levels in brain and lung. |
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