Anti-AGTRAP / ATRAP Antibody (clone 1G2)
Mouse Anti Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q6RW13 |
Predicted | Human |
Host | Mouse |
Clonality | Monoclonal |
Isotype | IgG1,k |
Clone Names | 1G2 |
Calculated MW | 17419 Da |
Dilution | ELISA, IHC-P (10 µg/ml), WB |
Gene ID | 57085 |
---|---|
Alias Symbol | AGTRAP |
Other Names | AGTRAP, ATRAP |
Target/Specificity | Human AGTRAP |
Reconstitution & Storage | Protein A purified |
Precautions | Anti-AGTRAP / ATRAP Antibody (clone 1G2) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AGTRAP |
---|---|
Synonyms | ATRAP |
Function | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II- stimulated transcriptional activity. |
Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles |
Tissue Location | Ubiquitous but more abundant in kidney, heart, pancreas and thyroid. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.