Anti-PNP / Nucleoside Phosphorylase Antibody (aa142-153)
Goat Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P00491 |
Predicted | Human |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 32118 Da |
Dilution | ELISA (1:128000), IHC-P (5 µg/ml), WB (0.03 - 0.1 µg/ml) |
Gene ID | 4860 |
---|---|
Alias Symbol | PNP |
Other Names | PNP, Inosine phosphorylase, NP, Nucleoside phosphorylase, PUNP, PRO1837 |
Target/Specificity | Human Nucleoside Phosphorylase / PNP |
Reconstitution & Storage | Immunoaffinity purified |
Precautions | Anti-PNP / Nucleoside Phosphorylase Antibody (aa142-153) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PNP |
---|---|
Synonyms | NP |
Function | Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (PubMed:9305964, PubMed:23438750). Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine (PubMed:9305964). |
Cellular Location | Cytoplasm. |
Tissue Location | Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology. |
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