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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-SDHAF1 Antibody (aa102-115)
Anti-SDHAF1 Antibody (aa102-115)
Goat Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | A6NFY7 |
| Predicted | Human, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 12806 Da |
| Dilution | ELISA (1:16000), IHC-P (5 µg/ml), WB (0.3 - 1 µg/ml) |
| Gene ID | 644096 |
|---|---|
| Alias Symbol | SDHAF1 |
| Other Names | SDHAF1, LYRM8, LYR motif-containing protein 8, SDH assembly factor 1 |
| Target/Specificity | Human SDHAF1. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-SDHAF1 Antibody (aa102-115) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SDHAF1 {ECO:0000303|PubMed:19465911, ECO:0000312|HGNC:HGNC:33867} |
|---|---|
| Function | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954417, PubMed:19465911). Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants (PubMed:24954417). May act together with SDHAF3 (PubMed:24954417). Contributes to iron-sulfur cluster incorporation into SDHB by binding to SDHB and recruiting the iron-sulfur transfer complex formed by HSC20, HSPA9 and ISCU through direct binding to HSC20 (PubMed:26749241). |
| Cellular Location | Mitochondrion matrix |
| Tissue Location | Ubiquitously expressed. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 467.50
Cat# ALS17911
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