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Anti-APOA1 / Apolipoprotein A 1 Antibody (clone 2G4)

Mouse Anti Human Monoclonal Antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P02647
Predicted Human
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names 2G4
Calculated MW 30778 Da
Dilution ELISA, IHC-P (1:50), WB (1:2000)
Additional Information
Gene ID 335
Alias Symbol APOA1
Other Names APOA1, ApoA-I, APOAI, Apolipoprotein A-I, Apolipoprotein A1, Apo-AI
Reconstitution & Storage Purified
PrecautionsAnti-APOA1 / Apolipoprotein A 1 Antibody (clone 2G4) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APOA1 (HGNC:600)
Function Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.
Cellular Location Secreted.
Tissue Location Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease
Research Areas
Citations (0)
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Discontinued
Cat# ALS18132
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