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Anti-GAS6 Antibody (N-Terminus)
Rabbit Anti Human Polyclonal Antibody
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Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q14393 |
| Predicted | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 74925 Da |
| Dilution | ELISA, IHC-P (10 µg/ml), WB (1 - 2 µg/ml) |
| Gene ID | 2621 |
|---|---|
| Alias Symbol | GAS6 |
| Other Names | GAS6, AXLLG, AXL stimulatory factor, AXSF, GAS-6, Growth arrest-specific 6 |
| Target/Specificity | GAS6 antibody is human, mouse and rat reactive. At least four isoforms of GAS6 are known to exist; this antibody will only detect the longest isoform. |
| Reconstitution & Storage | Immunoaffinity purified |
| Precautions | Anti-GAS6 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GAS6 (HGNC:4168) |
|---|---|
| Synonyms | AXLLG |
| Function | Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. |
| Cellular Location | Secreted. |
| Tissue Location | Plasma. Isoform 1 and isoform 2 are widely expressed, isoform 1 being expressed at higher levels than isoform 2 in most tissues. Isoform 2 is the predominant form in spleen |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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