Anti-OGG1 Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | O15527 |
Predicted | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 38782 Da |
Dilution | IHC-P (1:100), WB (1:200 - 1:1000) |
Gene ID | 4968 |
---|---|
Alias Symbol | OGG1 |
Other Names | OGG1, 8-oxoguanine DNA glycosylase, AP lyase, HMMH, N-glycosylase/DNA lyase, HOGG1, OGH1, OGG1 type 1f, MMH, MUTM |
Target/Specificity | Human OGG1 |
Reconstitution & Storage | Affinity purified |
Precautions | Anti-OGG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OGG1 |
---|---|
Synonyms | MMH, MUTM, OGH1 |
Function | DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. |
Cellular Location | Nucleus, nucleoplasm. Nucleus speckle. Nucleus matrix. Note=Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells [Isoform 2A]: Mitochondrion. |
Tissue Location | Ubiquitous. |
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