Anti-CLP / COTL1 Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q14019 |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Calculated MW | 15945 Da |
Dilution | ELISA, IHC-P (7.5 µg/ml), WB |
Gene ID | 23406 |
---|---|
Alias Symbol | COTL1 |
Other Names | COTL1, CLP, Coactosin-like protein |
Target/Specificity | Human CLP / COTL1 |
Reconstitution & Storage | Caprylic acid and ammonium sulfate precipitation |
Precautions | Anti-CLP / COTL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | COTL1 |
---|---|
Synonyms | CLP |
Function | Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis. |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Nucleus |
Tissue Location | Widely expressed with highest levels in placenta, lung, kidney and peripheral blood leukocytes and lower levels in brain, liver and pancreas. |
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