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Anti-GRIN1 / NMDAR1 Antibody
Rabbit Anti Human Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q05586 |
| Predicted | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 105373 Da |
| Dilution | IHC-P (1:100), WB |
| Gene ID | 2902 |
|---|---|
| Alias Symbol | GRIN1 |
| Other Names | GRIN1, GluN1, NMDAR1, NR1, MRD8, NMD-R1, NMDA receptor A1, NMDA1, NR1a, GluR zeta 1 |
| Target/Specificity | Human GRIN1 / NMDAR1 |
| Reconstitution & Storage | Affinity purified |
| Precautions | Anti-GRIN1 / NMDAR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GRIN1 |
|---|---|
| Synonyms | NMDAR1 |
| Function | Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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