NUDT8 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, IHC-P, E |
---|---|
Primary Accession | Q8WV74 |
Other Accession | NP_862826.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 25370 Da |
Antigen Region | 42-70 aa |
Gene ID | 254552 |
---|---|
Other Names | Nucleoside diphosphate-linked moiety X motif 8, mitochondrial, Nudix motif 8, 361-, NUDT8 |
Target/Specificity | This NUDT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human NUDT8. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | NUDT8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NUDT8 |
---|---|
Function | Acyl-CoA diphosphatase that mediates the hydrolysis of a wide range of CoA and CoA esters yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products (By similarity). Hydrolyzes short- and medium-chain acyl-CoAs, exhibiting the highest activity toward free CoA, hexanoyl-CoA, and octanoyl-CoA and the lowest activity against acetyl-CoA (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity). |
Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:Q9CR24}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (By similarity).
References
Gasmi, L., et al. Biochem. J. 357 (PT 1), 33-38 (2001) :
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