HCE Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IP |
---|---|
Primary Accession | O60942 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 68557 Da |
Gene ID | 8732 |
---|---|
Other Names | RNGTT |
Dilution | WB~~1/500-1/1000 IP~~N/A |
Format | Liquid |
Name | RNGTT |
---|---|
Synonyms | CAP1A |
Function | Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate. |
Cellular Location | Nucleus. |
Tissue Location | Isoform 1 and isoform 4 (at a lesser extent) are expressed in cerebrum, cerebellum, thyroid, lung, heart, liver, kidney, spleen, large intestine, testis, skin and muscle |

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