|Other Names||Meiotic recombination protein DMC1/LIM15 homolog, DMC1, DMC1H, LIM15|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.|
|Cellular Location||Nucleus. Chromosome.|
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Provided below are standard protocols that you may find useful for product applications.
DMC1 is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this protein is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes.
Volodin,A.A. J. Biol. Chem. 284 (3), 1495-1504 (2009)Hikiba,J.FEBS J. 276 (2), 457-465 (2009)Hikiba,J. Nucleic Acids Res. 36 (12), 4181-4190 (2008)
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