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EIF2AK2 Antibody (monoclonal) (M02)

Mouse monoclonal antibody raised against a partial recombinant EIF2AK2.

     
  • IF - EIF2AK2 Antibody (monoclonal) (M02) AT1871a
    Immunofluorescence of monoclonal antibody to EIF2AK2 on HeLa cell. [antibody concentration 30 ug/ml]
    detail
  • WB - EIF2AK2 Antibody (monoclonal) (M02) AT1871a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
    detail
  • WB - EIF2AK2 Antibody (monoclonal) (M02) AT1871a
    EIF2AK2 monoclonal antibody (M02), clone 1D11 Western Blot analysis of EIF2AK2 expression in K-562 ( (Cat # AT1871a )
    detail
  • WB - EIF2AK2 Antibody (monoclonal) (M02) AT1871a
    Western Blot analysis of EIF2AK2 expression in transfected 293T cell line by EIF2AK2 monoclonal antibody (M02), clone 1D11.

    Lane 1: EIF2AK2 transfected lysate(62.1 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • IHC - EIF2AK2 Antibody (monoclonal) (M02) AT1871a
    Immunoperoxidase of monoclonal antibody to EIF2AK2 on formalin-fixed paraffin-embedded human adrenal gland. [antibody concentration 1.5 ug/ml]
    detail
  • E - EIF2AK2 Antibody (monoclonal) (M02) AT1871a
    Detection limit for recombinant GST tagged EIF2AK2 is approximately 0.03ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, E
Primary Accession P19525
Other Accession NM_002759
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 1D11
Calculated MW 62094 Da
Additional Information
Gene ID 5610
Other Names Interferon-induced, double-stranded RNA-activated protein kinase, Eukaryotic translation initiation factor 2-alpha kinase 2, eIF-2A protein kinase 2, Interferon-inducible RNA-dependent protein kinase, P1/eIF-2A protein kinase, Protein kinase RNA-activated, PKR, Protein kinase R, Tyrosine-protein kinase EIF2AK2, p68 kinase, EIF2AK2, PKR, PRKR
Target/Specificity EIF2AK2 (NP_002750, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsEIF2AK2 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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References

1.PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis.Cheng X, Bennett RL, Liu X, Byrne M, Stratford May WBlood Cancer J. 2013 Sep 6;3:e144. doi: 10.1038/bcj.2013.42.2.PKR regulates proliferation, differentiation and survival of murine hematopoietic stem/progenitor cells.Liu X, Bennett RL, Cheng X, Byrne M, Reinhard MK, May WS JrBlood. 2013 Feb 14.3.Increased Expression of the dsRNA-Activated Protein Kinase PKR in Breast Cancer Promotes Sensitivity to Doxorubicin.Bennett RL, Carruthers AL, Hui T, Kerney KR, Liu X, May WS Jr.PLoS One. 2012;7(9):e46040. doi: 10.1371/journal.pone.0046040. Epub 2012 Sep 24.

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$ 350.00
Cat# AT1871a
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