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CACNB2 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CACNB2.

     
  • WB - CACNB2 Antibody (monoclonal) (M01) AT1367a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.53 KDa) .
    detail
  • WB - CACNB2 Antibody (monoclonal) (M01) AT1367a
    CACNB2 monoclonal antibody (M01), clone 6C1. Western Blot analysis of CACNB2 expression in PC-12 ( (Cat # AT1367a )
    detail
  • WB - CACNB2 Antibody (monoclonal) (M01) AT1367a
    CACNB2 monoclonal antibody (M01), clone 6C1 Western Blot analysis of CACNB2 expression in Jurkat ( (Cat # AT1367a )
    detail
  • WB - CACNB2 Antibody (monoclonal) (M01) AT1367a
    CACNB2 monoclonal antibody (M01), clone 6C1. Western Blot analysis of CACNB2 expression in NIH/3T3 ( (Cat # AT1367a )
    detail
  • E - CACNB2 Antibody (monoclonal) (M01) AT1367a
    Detection limit for recombinant GST tagged CACNB2 is approximately 0.1ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q08289
Other Accession NM_201596
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1 Kappa
Clone Names 6C1
Calculated MW 73581 Da
Additional Information
Gene ID 783
Other Names Voltage-dependent L-type calcium channel subunit beta-2, CAB2, Calcium channel voltage-dependent subunit beta 2, Lambert-Eaton myasthenic syndrome antigen B, MYSB, CACNB2, CACNLB2, MYSB
Target/Specificity CACNB2 (NP_963890, 213 a.a. ~ 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCACNB2 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a subunit of a voltage-dependent calcium channel protein which is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome which is an autoimmune disorder. Mutations in this gene are associated with Brugada symdrome. Alternatively spliced variants have been identified for this gene.

References

Mutations in the Cardiac L-Type Calcium Channel Associated with Inherited J Wave Syndromes and Sudden Cardiac Death. Burashnikov E, et al. Heart Rhythm, 2010 Sep 2. PMID 20817017.An approach based on a genome-wide association study reveals candidate loci for narcolepsy. Shimada M, et al. Hum Genet, 2010 Oct. PMID 20677014.Blood pressure and hypertension are associated with 7 loci in the Japanese population. Takeuchi F, et al. Circulation, 2010 Jun 1. PMID 20479155.Recapitulation of two genomewide association studies on blood pressure and essential hypertension in the Korean population. Hong KW, et al. J Hum Genet, 2010 Jun. PMID 20414254.Genome-wide association study of bipolar I disorder in the Han Chinese population. Lee MT, et al. Mol Psychiatry, 2010 Apr 13. PMID 20386566.

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$ 350.00
Cat# AT1367a
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Availability: 7-10 days
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